Jump down to recent developments, below.
Background:
The National Institutes of Health is the primary federal agency responsible for biomedical and public health research in the United States. It is part of the Department of Health and Human Services (HHS).
Today NIH is the largest funder of biomedical research in the world.
NIH consists of 27 institutes and centers, each focused on particular diseases, body systems, or research areas. The largest and most well-known include the National Cancer Institute (NCI), the National Institute of Allergy and Infectious Diseases (NIAID), the National Heart, Lung, and Blood Institute (NHLBI), and the National Institute of Mental Health (NIMH).
NIH’s core mission is to seek fundamental knowledge about living systems and apply that knowledge to enhance health and reduce illness. It pursues this through two main channels — intramural research conducted by NIH scientists on its Bethesda, MD campus, and extramural research through grants and contracts to universities, medical schools, and research institutions across the country and abroad. The vast majority of its budget, roughly 80-85%, goes to extramural grants.
NIH’s annual budget is about $47 to 49 billion supporting around 300,000 researchers at over 2,500 institutions nationwide. Congress rejected the Trump Administration’s proposed 40 percent cut in NIH, however the Administration cut back new grants and competitive renewals in FY 2025. It remains to be seen whether they similarly hold back congressionally appropriated funds during FY 2026.
It is illegal for the President to impound—refuse to spend—congressionally appropriated funds. See our explanation HERE.
Recent Developments:
Fri, Sept 25, 2026:
Murray, Baldwin Lead Colleagues in Demanding Vought Abandon Any and All Plans to Exert Political Control Over NIH Funding - Sen. Approps
Wed, Sept 23, 2026:
Murray on Trump Admin Scrapping Plans for Executive Order to Empower Russ Vought to Kill NIH Research - Senate Approps
Trump administration backing off NIH grant order amid pushback - Semafor
Tues, Sept 22, 2026:
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Fri, Sept 18, 2026:
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Thurs, May 21, 2026:
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Sat, April 11, 2026:
Tues, March 17, 2026:
NIH Director Claims Administration Will Spend Appropriated Funds: National Institutes of Health Director Jay Bhattacharya promised a House Appropriations subcommittee on Tuesday that, despite the sluggish pace of grant awards, the agency will spend its full budget by the end of the 2026 fiscal year. [However,] roughly halfway through the fiscal year, the agency has awarded 74% fewer competitive, or new, awards than the average for that same period during 2021-2024, according to an analysis by Johns Hopkins researchers. - Stat
Mon, Nov 17, 2025:
Thurs, Oct 16, 2025:
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Thurs, Aug 21, 2025:
Tues, Aug 5, 2025:
Wed, July 30, 2025:
Fri, July 18, 2025:
How Changes to Funding for the NIH and Changes in the FDA’s Review Times Would Affect the Development of New Drugs – CBO
The Trump administration’s proposed cuts at the National Institutes of Health and Food and Drug Administration could lower the number of new drugs that come to market in the next three decades, according to a Congressional Budget Office analysis released Friday.
Wed, July 16, 2025:
Wed, June 25, 2025:
Despite the NIH memo and court rulings in favor of scientists, it’s not clear whether researchers can quickly get back to work because the Trump administration is reportedly still deciding on its next steps. “Researchers haven’t yet been able to access funds covered by the ruling as part of the order, and the likelihood that the government will appeal or seek to halt the order leaves the outlook murky,” Axios reported yesterday. And if or when the funding flows again, scientists say that their work has already been affected, in some cases making it hard to salvage their studies. – FT
Tues, June 24, 2025:
Mon, June 10, 2025:
“Ending a $5 million research study when it is 80% complete does not save $1 million, it wastes $4 million,” they write. They add that the decisions risk people’s health: “NIH trials are being halted without regard to participant safety, abruptly stopping medications or leaving participants with unmonitored device implants.”
The letter warns that the “unprecedented reduction in NIH spending” is not a move toward greater efficiency “but rather a dramatic reduction in life-saving research” and a violation of Bhattacharya’s duty to spend congressionally appropriated funds for NIH research.
Wed, May 28, 2025:
Scientists made a breakthrough in the treatment of brain diseases. What they did: Created gene delivery systems, or “trucks,” which can target different cell types in the brain and spinal cord. It means treatments can reach specific cells. Why it matters: It may lead to new therapies for diseases like Parkinson’s and Alzheimer’s, if the project’s federal funding continues. – WP
Wed, April 16, 2025:
Women, minorities fired in purge of NIH science review boards; Scientists, with expertise in fields that include mental health, cancer and infectious disease, typically serve five-year terms and were not given a reason for their dismissal. – WP
Mon, April 14, 2025:
The cost of Trump and Kennedy’s cuts at NIH is already adding up; The cuts will crush U.S. leadership in biomedicine and put millions of American lives at risk. – Diana DeGette/Fred Upton
Mon, April 7, 2025:

